肿瘤假体置换术是侵袭性或恶性肿瘤切除术后主要的重建方式。综合治疗对骨肿瘤良好控制的前提下,肿瘤假体置换保留了患者肢体和部分功能,提高其生活质量。随着假体使用的广泛,长期随访中其并发症报道逐渐增多。通过对文献回顾性研究,将并发症主要分为两种类型,即肿瘤相关和非肿瘤相关并发症。本研究旨在对并发症进行分析研究。 Tumor prosthesis applies to reconstruction after invasive or malignant neoplasm’s resection. Multidiscipline treatment is known to local and system control. The desirable limb-saving condi-tion leads to more patients undergoing arthroplasty. The use of tumor prosthesis is accessible because of high survival rate. The complications of arthroplasty attach growing attention in the long- term follow-up. There are two types of failure in the retrospective study, tumor-related and non- tumor-related complications. This study is aimed to classify complications and summarize diagnosis and treatment.
关节置换,骨肿瘤,并发症,翻修术, Arthroplasty Bone Neoplasms Complication Revision肿瘤假体置换术后相关并发症分析
参考文献 (References)ReferencesAnderson, M.E. (2016) Update on Survival in Osteosarcoma. Orthopedic Clinics of North America, 47, 283-292.
<br>https://doi.org/10.1016/j.ocl.2015.08.022Ferrari, S. and Serra, M. (2015) An Update on Chemotherapy for Osteosarcoma. Expert Opinion on Pharmacotherapy, 16, 2727-2736. <br>https://doi.org/10.1517/14656566.2015.1102226Lopresti, M., Rancati, J., Farina, E., et al. (2015) Rehabilitation Pathway after Knee Arthroplasty with Mega Prosthesis in Osteosarcoma. Recenti Progressi in Medicina, 106, 385-392.Li, D., Ma, H., Zhang, W., et al. (2015) Analysis of Implant-Related Complications after Hinge Knee Replacement for Tumors around the Knee. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, 29, 936-940.Houdek, M.T., Wagner, E.R., Wilke, B.K., et al. (2016) Long Term Outcomes of Cemented Endoprosthetic Reconstruction for Periarticular Tumors of the Distal Femur. Knee, 23, 167-172. <br>https://doi.org/10.1016/j.knee.2015.08.010Bacci, G., Forni, C., Longhi, A., et al. (2007) Local Recurrence and Local Control of Non-Metastatic Osteosarcoma of the Extremities: A 27-Year Experience in a Single Institution. Journal of Surgical Oncology, 96, 118-123.
<br>https://doi.org/10.1002/jso.20628Palmerini, E., Jones, R.L., Marchesi, E., et al. (2016) Gemcitabine and Docetaxel in Relapsed and Unresectable High-Grade Osteosarcoma and Spindle Cell Sarcoma of Bone. BMC Cancer, 16, 280.
<br>https://doi.org/10.1186/s12885-016-2312-3The ESMO/European Sarcoma Network Working Group (2014) Bone Sarcomas: ESMO Clinical Practice Guidelines for Diagnosis, Treatment and Follow-up. Annals of Oncology, 25, iii113-iii123.
<br>https://doi.org/10.1093/annonc/mdu256Rothermundt, C., Seddon, B.M., Dileo, P., et al. (2016) Follow-up Practices for High-Grade Extremity Osteosarcoma. BMC Cancer, 16, 301. <br>https://doi.org/10.1186/s12885-016-2333-yKang, X., Huang, Z., Shi, A., et al. (2016) Deficiencies in the Diagnosis and Treatment of Pulmonary Metastatic Osteosarcoma: A Chinese Multidisciplinary Survey. Zhongguo Fei Ai Za Zhi, 19, 153-160.Puri, A., Gulia, A., Hawaldar, R., et al. (2014) Does Intensity of Surveillance Affect Survival after Surgery for Sarcomas? Results of a Randomized Noninferiority Trial. Clinical Orthopaedics and Related Research, 472, 1568-1575.
<br>https://doi.org/10.1007/s11999-013-3385-9Chou, A.J., Gupta, R., Bell, M.D., et al. (2013) Inhaled Lipid Cisplatin (ILC) in the Treatment of Patients with Relapsed/Progressive Osteosarcoma Metastatic to the Lung. Pediatric Blood & Cancer, 60, 580-586.
<br>https://doi.org/10.1002/pbc.24438Yu, L., Cai, L., Hu, H., et al. (2014) Experiments and Synthesis of Bone-Targeting Epirubicin with the Water-Soluble Macromolecular Drug Delivery Systems of Oxidized-Dextran. Journal of Drug Targeting, 22, 343-351.
<br>https://doi.org/10.3109/1061186X.2013.877467Gosiengfiao, Y., Reichek, J., Woodman, J., et al. (2012) Gemcitabine with or without Docetaxel and Resection for Recurrent Osteosarcoma: The Experience at Children’s Memorial Hospital. Journal of Pediatric Hematology/Oncology, 34, e63-e65.Machak, G.N., Polotskiĭ, B.E., Meluzova, O.M., et al. (2010) Treatment of Relapsed Osteosarcoma. Role of Chemotherapy Using Ifosamide and Carboplatin. Voprosy Onkologii, 56, 220-225.Dinçbaş, F.O., Koca, S., Mandel, N.M., et al. (2005) The Role of Preoperative Radiotherapy in nonmetAstatic High-Grade Osteosarcoma of the Extremities for Limb-Sparing Surgery. International Journal of Radiation Oncology*Biology*Physics, 62, 820-828. <br>https://doi.org/10.1016/j.ijrobp.2004.11.006Fagioli, F., Aglietta, M., Tienghi, A., Ferrari, S., et al. (2002) High-Dose Chemotherapy in the Treatment of Relapsed Osteosarcoma: An Italian Sarcoma Group Study. Journal of Clinical Oncology, 20, 2150-2156.
<br>https://doi.org/10.1200/JCO.2002.08.081Kushnir, I., Kolander, Y., Bickels, J., et al. (2014) Is It Important to Maintain High-Dose Intensity Chemotherapy in the Treatment of Adults with Osteosarcoma. Medical Oncology, 31, 936. <br>https://doi.org/10.1007/s12032-014-0936-1Wirganowicz, P.Z., Eckardt, J.J., Dorey, F.J., et al. (1999) Etiology and Results of Tumor Endoprosthesis Revision Surgery in 64 Patients. Clinical Orthopaedics and Related Research, 358, 64-74.Hardes, J., Ahrens, H., Gosheger, G., et al. (2014) Management of Complications in Megaprostheses. Der Unfallchirurg, 117, 607-613. <br>https://doi.org/10.1007/s00113-013-2477-zPajarinen, J., Lin, T.H., Nabeshima, A., et al. (2016) Mesenchymal Stem Cells in the Aseptic Loosening of Total Joint Replacements. Journal of Biomedical Materials Research Part A, 105, 1195-1207.Maloney, W.J. and Smith, R.L. (1996) Periprosthetic Osteolysis in Total Hip Arthroplasty: The Role of Particulate Wear Debris. Instructional Course Lectures, 45, 171-182.Kempthorne, J.T., Ailabouni, R., Raniga, S., Hammer, D. and Hooper, G. (2015) Occult Infection in Aseptic Joint Loosening and the Diagnostic Role of Implant Sonication. BioMed Research International, 2015, Article ID: 946215.
<br>https://doi.org/10.1155/2015/946215Aibinder, W.R., Schoch, B., Schleck, C., et al. (2017) Revisions for Aseptic Glenoid Component Loosening after Anatomic Shoulder Arthroplasty. Journal of Shoulder and Elbow Surgery, 26, 443-449.Jeys, L.M., Kulkarni, A., Grimer, R.J., et al. (2008) Endoprosthetic Reconstruction for the Treatment of Musculoskeletal Tumors of the Appendicular Skeleton and Pelvis. The Journal of Bone and Joint Surgery-America Volume, 90, 1265-1271. <br>https://doi.org/10.2106/JBJS.F.01324Myers, G.J., Abudu, A.T., Carter, S.R., et al. (2007) Endoprosthetic Replacement of the Distal Femur for Bone Tumours: Long-Term Results. The Journal of Bone and Joint Surgery-British Volume, 89, 521-526.
<br>https://doi.org/10.1302/0301-620X.89B4.18631Dowsey, M.M. and Choong, P.F. (2008) Obesity Is a Major Risk Factor for Prosthetic Infection after Primary Hip Arthroplasty. Clinical Orthopaedics and Related Research, 466, 153-158. <br>https://doi.org/10.1007/s11999-007-0016-3Morii, T., Yabe, H., Morioka, H., et al. (2010) Postoperative Deep Infection in Tumor Endoprosthesis Reconstruction around the Knee. Journal of Orthopaedic Science, 15, 331-339. <br>https://doi.org/10.1007/s00776-010-1467-zMcDonald, M., Grabsch, E., Marshall, C., et al. (1998) A Single- versus Multiple-Dose Antimicrobial Prophylaxis for Major Surgery: A Systematic Review. ANZ Journal of Surgery, 68, 388-396.
<br>https://doi.org/10.1111/j.1445-2197.1998.tb04785.xPeel, T., May, D., Buising, K., et al. (2014) Infective Complications Following Tumour Endoprosthesis Surgery for Bone and Soft Tissue Tumours. European Journal of Surgical Oncology, 40, 1087-1094.Juul, R., Fabrin, J., Poulsen, K., et al. (2016) Use of a New Knee Prosthesis as an Articulating Spacer in Two-Stage Revision of Infected Total Knee Arthroplasty. Knee Surgery & Related Research, 28, 239-244.
<br>https://doi.org/10.5792/ksrr.2016.28.3.239Ehlinger, M., Adam, P., Di Marco, A., et al. (2011) Periprosthetic Femoral Fractures Treated by Locked Plating: Feasibility Assessment of the Mini-Invasive Surgical Option. A Prospective Series of 36 Fractures. Orthopaedics & Traumatology: Surgery & Research, 97, 622-628. <br>https://doi.org/10.1016/j.otsr.2011.01.017Giesinger, K., Ebneter, L., Day, R.E., et al. (2014) Can Plate Osteosynthesis of Periprosthethic Femoral Fractures Cause Cement Mantle Failure around a Stable Hip Stem? A Biomechanical Analysis. The Journal of Arthroplasty, 29, 1308-1312. <br>https://doi.org/10.1016/j.arth.2013.12.015Rorabeck, C.H. and Taylor, J.W. (1999) Periprosthetic Fractures of the Femur Complicating Total Knee Arthroplasty. Orthopedic Clinics of North America, 30, 265-277.Jentzsch, T., Erschbamer, M., Seeli, F., et al. (2013) Extensor Function after Medial Gastrocnemius Flap Reconstruction of the Proximal Tibia. Clinical Orthopaedics and Related Research, 471, 2333-2339.
<br>https://doi.org/10.1007/s11999-013-2851-8Althausen, P.L., Lee, M.A., Finkemeier, C.G., et al. (2003) Operative Stabilization of Supracondylar Femur Fractures above Total Knee Arthroplasty: A Comparison of Four Treatment Methods. The Journal of Arthroplasty, 18, 834-839.
<br>https://doi.org/10.1016/S0883-5403(03)00339-5Gosheger, G., Gebert, C., Ahrens, H., et al. (2006) Endoprosthetic Reconstruction in 250 Patients with Sarcoma. Clinical Orthopaedics and Related Research, 450, 164-171.Dobbs, R.E., Hanssen, A.D., Lewallen, D.G. and Pagnano, M.W. (2005) Quadriceps Tendon Rupture after Total Knee Arthroplasty. Prevalence, Complications, and Outcomes. The Journal of Bone and Joint Surgery-America Volume, 87, 37-45.