目的:研究应用补片加固食管胃吻合口的效果。方法:选取新鲜离体猪食管及猪胃制作食管胃吻合模型,第一部试验,找到模型承受内部压力时吻合口薄弱点,第二部试验,通过测定爆破压,评价奈维对吻合口薄弱点的加固作用。结果:吻合口薄弱位置位于食管肌层,加奈维组吻合口模型的爆破压高于无奈维加固组的爆破压(P < 0.001)。结论:试验的结果表明,在体外模型中使用奈维可以起到加固吻合口的作用,应用奈维加固吻合口薄弱部位可能减少吻合口瘘的发生。
Objective: To study the effect of reinforcement of esophagogastric anastomosis by Neoveil
®. Methods: The esophagogastric anastomosis model was made by fresh isolated pig esophagus and stomach. In Experiment 1, the weak point of the model under internal pressure was clarified; in Experiment 2, we evaluated the effect of using Neoveil
® to reinforce the weak point of the anastomosis by measuring the burst pressure. Results: The weak point of the anastomosis was the esophageal muscular layer; the burst pressure of anastomosis in group with Neoveil
® was significantly higher than the group with no Neoveil
® reinforcement (P < 0.001). Conclusion: These findings suggest that the use of Neoveil
® as a buttressing material can reinforce the anastomosis in this ex vivo model; reinforcement of the weak point of the anastomosis with Neoveil
® may lead to fewer anastomotic leaks.
何 明,刘佳坤,牛林鹏,李保重,赵继东,马国刚. 应用奈维加固食管胃吻合口的试验研究An Experimental Study on Reinforcement of Esophagogastric Anastomosis by Neoveil®[J]. 临床医学进展, 2019, 09(03): 209-214. https://doi.org/10.12677/ACM.2019.93033
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