龙葵素是一种重要的糖苷生物碱,具有多种生物学作用,能对多种疾病起到防治的作用,其中包括抗肿瘤作用。龙葵素在抗肿瘤作用从细胞和分子途径诱导细胞的凋亡和自噬,使癌细胞的迁移、浸润、血管发生一起转移能力受到抑制。因此,本文就龙葵素对各种癌细胞的抑制作用及其作用机制进行了综述。<br/>Solanine is an important glycoalkaloid, with a variety of biological effects. It plays a role in pre-vention and treatment of many diseases, including its anti-tumor effect. Solanine exhibits its an-ti-tumor effect through regulation several cellular and molecular pathways which induce cell apoptosis and autophagy, and inhibit cancer cells’ migration, invasion, angiogenesis and metastasis. Therefore, anti-cancer effects of solanine and its mechanism are reviewed in this article.
李兰香,熊兴耀,杨 青. 龙葵素抗肿瘤作用研究进展 Progress of Anti-Cancer Function of Solanine[J]. 食品与营养科学, 2016, 05(02): 26-30. http://dx.doi.org/10.12677/HJFNS.2016.52004
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