缺血性脑卒中(Ischemic stroke IS)是临床常见病,具有高发病率、高死亡率、高致残率的特点,占脑卒中的70%~80%,给家庭及社会带来沉重的负担。面对其预防及治疗效果不满意、发病机制复杂的现状,利用中医体质识别及目前现有的辅助检查相结合的手段,可以为临床中预防及治疗缺血性脑卒中提供新方向。本文通过对近年来缺血性脑卒中、中医体质和经颅多普勒超声(transcranial Doppler, TCD)改变以及其三者之间的相关研究进展进行分析和总结,探讨缺血性脑卒中患者中医体质和TCD所示颅内血管改变的相关性。 Ischemic stroke is a common clinical disease with high morbidity, high mortality and high disability rate, accounting for 70%~80% of stroke. It is a serious threat to human health, and brings the family and society heavy burden. By means of combining constitution of TCM and clinical assistant examination can provide new direction for prevention and treatment of ischemic stroke, facing the present conduction—unsatisfactory prevention and treatment effect, the complicated pathogenesis. This essay analyzes and summarizes the recent advances in ischemic stroke, TCM constitution and intracranial vascular changes detected by transcranial Doppler, and the related research progress between them, and aims to investigate the correlation between TCM constitution and intracranial vascular changes detected by transcranial Doppler in ischemic stroke patients.
中医体质,缺血性脑卒中,TCD改变, Constitution of TCM Ischemic Stroke Intracranial Vascular Changes Detected by TCD缺血性脑卒中TCD改变与中医体质相关性的研究进展
付信晓,黎明全. 缺血性脑卒中TCD改变与中医体质相关性的研究进展Research Progress on Correlation between TCD Changes and Constitution of TCM in Ischemic Stroke[J]. 中医学, 2018, 07(01): 109-113. http://dx.doi.org/10.12677/TCM.2018.71017
参考文献 (References)ReferencesYang, G., Wang, Y., Zeng, Y., et al. (2013) Rapid Health Transition in China, 1990-2010: Findings from the Global Burden of Disease Study 2010. Lancet, 381, 1987-2015. <br>https://doi.org/10.1016/S0140-6736(13)61097-1王琦. 中医体质学[M]. 北京: 人民卫生出版社, 2005: 22-45.朱燕波, 王琦, 吴承玉, 等. 18805例中国成年人中医体质类型与超重肥胖关系的Logistic回归分析[J]. 中西医结合学报, 2010, 8(11): 1023-1028.王陇德. 中国脑卒中防治报告[M]. 北京: 中国协和医科大学出版社, 2015.赵冬. 我国人群脑卒中发病率、死亡率的流行病学研究[J]. 中华流行病学杂志, 2003, 23(3): 236-239.马卫琴, 李碧青, 聂志红, 等. 中风先兆与中医体质相关性探析[J]. 中国中医急症, 2012, 21(2): 243-243.李柱, 王清峰, 吴银玲, 等. 200例急性缺血性中风(中经络)患者中医证候与中医体质辨识相关性研究[J]. 中医临床研究, 2016, 8(17): 15-17.贾爱明, 胡文梅, 张红, 等. 620例缺血性中风恢复期患者体质与证候研究[J]. 中国中医药信息杂志, 2013, 20(6): 14-16.王洪真, 魏咏梅, 孙霞, 等. 186例复发性脑卒中患者体质特征研究[J]. 新中医, 2014(2): 50-53.孔燕莹, 王远国, 苏健淦, 等. 202例脑血管病后遗症患者中医体质类型分析[J]. 中国民族民间医药, 2017(11): 10-11.Zhao, L., Barlinn, K., Sharma, V.K., et al. (2011) Velocity Criteria for Intracranial Stenosis Revisited. Stroke: A Journal of Cerebral Circulation, 42, 3429-3434. <br>https://doi.org/10.1161/STROKEAHA.111.621235Feldmann, E., Wilterdink, J.L., Kosinski, A., et al. (2007) Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) Trial Investigators. The Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) trial. Neurology, 68, 2099-2106. <br>https://doi.org/10.1212/01.wnl.0000261488.05906.c1中华医学会神经病学分会. 中国脑血管超声临床应用指南[J]. 中华神经科杂志, 2016, 49(7): 505-506.Tonkin, H. (1998) Large Infarcts in the Middle Cerebral Artery Territory. Etiology and Outcome Patterns. Neurology, 50, 341-350. <br>https://doi.org/10.1212/WNL.50.2.341刘承基, 凌锋. 脑脊髓血管外科学[M]. 北京: 中国科学技术出版社, 2013.唐旸烁, 华扬. 颈动脉支架置入后再狭窄的危险因素及超声评估的研究进展[J]. 中国脑血管病杂志, 2011, 8(11): 599-602.Kumako, V., Derex, L., Blanclasserre, K., et al. (2014) Cerebral Infarction after Ovarian Hyperstimulation in the Era of Thrombolysis. Revue Neurologique, 170, 197-204. <br>https://doi.org/10.1016/j.neurol.2013.10.010李康, 姜世峰, 于书壮, 等. CTA、TCD及DSA用于临床诊断颅内血管狭窄的准确性差异分析[J]. 临床合理用药杂志, 2015(4): 144.Karandashova, S., Florova, G., Azghani, A.O., et al. (2013) Intrapleural Adenoviral Delivery of Human Plasminogen Activator Inhibitor-1 Exacerbates Tetracycline-Induced Pleural Injury in Rabbits. American Journal of Respiratory Cell & Molecular Biology, 48, 44-52. <br>https://doi.org/10.1165/rcmb.2012-0183OC杨利杰, 李红艳, 范丹. 经颅多普勒在急性脑梗死静脉溶栓治疗中的应用观察[J]. 中国现代药物应用, 2013, 7(20): 13-14.尹莲花, 黄守清, 许艺惠. 300例高血压前期患者中医体质与动脉硬化程度的相关性研究[J]. 世界中医药, 2015(9): 1424-1426.周华, 武彦, 戎靖枫, 等. 原发性高血压中医体质与颈动脉粥样硬化的相关性研究[J]. 中西医结合心脑血管病杂志, 2010, 8(2): 127-129.范莹, 陈柏楠, 张玥. 闭塞性动脉硬化症中医体质分布特点与相关影响因素研究[J]. 中国中西医结合外科杂志, 2014(4): 363-367.孟晓嵘, 骆杰伟, 郑姜钦, 等. 2型糖尿病合并肿瘤患者中医体质类型及与糖类抗原CA199的相关性研究[J]. 中华中医药杂志, 2014(6): 1963-1965.丁春丽, 侯丽辉, 郝松莉, 等. 多囊卵巢综合征患者中医体质与性激素、脂代谢的相关性分析[J]. 中医杂志, 2016, 57(15): 1303-1307.匡调元. 人体体质学[M]. 上海: 上海科学技术出版社, 2003: 2203.邱笑琼, 杨军, 陆川, 等. 297例缺血性脑血管病患者中医体质和脑血管造影分析[J]. 中国中医急症, 2015, 24(3): 457-460.赖少兰, 袁茂华, 张彩艳. 脑卒中中医体质与脑血流动力学的相关性研究[J]. 中医药导报, 2013(3): 13-15.