肠球菌是一种广泛存在于自然环境中的乳酸菌(LAB),同时也可寄居于人和动物的肠道内。肠球菌因其在健康促进方面的作用和食品工业中的技术优势等特性,它被广泛应用在发酵生产和药物中。肠球菌可作发酵剂、发酵附加物及益生菌。益生菌用于治疗腹泻、抗生素相关腹泻或肠易激综合征,降低胆固醇水平或提高宿主免疫力。本文就肠球菌的有益性进行综述。
Enterococci are ubiquitous lactic acid bacteria (LAB) that exist widely in food and the natural environment, and they can also reside in the gastrointestinal tract of humans and animals. Enterococci are widely used in fermentation production and medicine due to their role in health promotion and technical advantages in the food industry. For example, Enterococci can be used as starters, fermentation additives and probiotics. Probiotics are used to treat various kinds of diarrhea, including antibiotic-related diarrhea and irritable bowel syndrome. Moreover, Enterococci are able to lower cholesterol levels and improve hosts’ immunity. This review summarizes the benefits of Enterococci.
Life Sciences College, Sichuan University, Chengdu Sichuan
Received: Aug. 4th, 2020; accepted: Aug. 17th, 2020; published: Aug. 24th, 2020
ABSTRACT
Enterococci are ubiquitous lactic acid bacteria (LAB) that exist widely in food and the natural environment, and they can also reside in the gastrointestinal tract of humans and animals. Enterococci are widely used in fermentation production and medicine due to their role in health promotion and technical advantages in the food industry. For example, Enterococci can be used as starters, fermentation additives and probiotics. Probiotics are used to treat various kinds of diarrhea, including antibiotic-related diarrhea and irritable bowel syndrome. Moreover, Enterococci are able to lower cholesterol levels and improve hosts’ immunity. This review summarizes the benefits of Enterococci.
参考文献ReferencesFAO/WHO (2002) Guidelines for the Evaluation of Probiotics in Food: Report of a Joint FAO/WHO Working Group on Drafting Guidelines for the Evaluation of Probiotics in Food.魏明颖, 王玉涵, 杨倩, 贾丽娜. 肠道益生菌功能特性研究进展[J]. 粮食与油脂, 2020, 33(4): 14-16.Higuita, N.I.A. and Huycke, M.M. (2014) Enterococcal Disease, Epidemiology, and Implications for Treatment.Franz, C.M.A.P., Huch, M., Abriouel, H., Holzapfel, W.H. and Galvez, A. (2011) Enterococci as Probiotics and Their Implications in Food Safety. International Journal of Food Microbiology, 151, 125-140.
<br>https://doi.org/10.1016/j.ijfoodmicro.2011.08.014Braïek, O.B. and Smaoui, S. (2019) Enterococci: Between Emerging Pathogens and Potential Probiotics. BioMed Research International, 2019, Article ID: 5938210. <br>https://doi.org/10.1155/2019/5938210Achemchem, F., Abrini, J., Martínezbueno, M., Valdivia, E. and Ma-queda, M. (2006) Control of Listeria monocytogenes in Goat’s Milk and Goat’s Jben by the Bacteriocinogenic Entero-coccus faecium F58 Strain. Journal of Food Protection, 69, 2370-2376. <br>https://doi.org/10.4315/0362-028X-69.10.2370Khan, H., et al. (2010) Enterocins in Food Preservation. In-ternational Journal of Food Microbiology, 141, 1-10.
<br>https://doi.org/10.1016/j.ijfoodmicro.2010.03.005Al Atya, A.K., et al. (2016) Anti-MRSA Activities of En-terocins DD28 and DD93 and Evidences on Their Role in the Inhibition of Biofilm Formation. Frontiers in Microbiology, 7, 817. <br>https://doi.org/10.3389/fmicb.2016.00817Parte, A.C. (2014) LPSN—List of Prokaryotic Names with Standing in Nomenclature. Nucleic Acids Research, 42, D613-D616. <br>https://doi.org/10.1093/nar/gkt1111Jin, D., et al. (2017) Enterococcus wangshanyuanii sp. nov., Isolated from Faeces of Yaks (Bos grunniens). International Journal of Systematic and Evolutionary Microbiology, 67, 5216-5221. <br>https://doi.org/10.1099/ijsem.0.002447Kadri, Z., Spitaels, F., Cnockaert, M., Praet, J., El Farricha, O., Swings, J., et al. (2015) Enterococcus bulliens sp. nov., a Novel Lactic Acid Bacterium Isolated from Camel Milk. Antonie van Leeuwenhoek, 108, 1257-1265.
<br>https://doi.org/10.1007/s10482-015-0579-zShewmaker, P.L., Steigerwalt, A.G., Nicholson, A.C., Carvalho, M.D.G.S., Facklam, R.R., Whitney, A.M., et al. (2011) Reevaluation of the Taxonomic Status of Recently Described Species of Enterococcus: Evidence that E. thailandicus Is a Senior Subjective Synonym of “E. sanguinicola” and Con-firmation of E. caccae as a Species Distinct from E. silesiacus. Journal of Clinical Microbiology, 49, 2676-2679. <br>https://doi.org/10.1128/JCM.00399-11Harada, T., Dang, V.C., Nguyen, D.P., Nguyen, T.A.D., Sakamoto, M., Ohkuma, M., et al. (2016) Enterococcus saigonensis sp. nov., Isolated from Retail Chicken Meat and Liver. Inter-national Journal of Systematic and Evolutionary Microbiology, 66, 3779-3785. <br>https://doi.org/10.1099/ijsem.0.001264Graham, K., Stack, H. and Rea, R. (2020) Safety, Beneficial and Technological Properties of Enterococci for Use in Functional Food Applications—A Review. Critical Reviews in Food Science and Nutrition, 10, 1-26.
<br>https://doi.org/10.1080/10408398.2019.1709800Wunderlich, P.F., et al. (1989) Double-Blind Report on the Efficacy of Lactic Acid-Producing Enterococcus SF68 in the Prevention of Antibiotic-Associated Diarrhoea and in the Treatment of Acute Diarrhoea. The Journal of International Medical Research, 17, 333-338. <br>https://doi.org/10.1177/030006058901700405Franz, C.M.A.P., et al. (2011) Enterococci as Probiotics and Their Implications in Food Safety. International Journal of Food Microbiology, 151, 125-140. <br>https://doi.org/10.1016/j.ijfoodmicro.2011.08.014Avram-Hananel, L., Stock, J., Parlesak, A., Bode, C. and Schwartz, B. (2010) E Durans Strain M4-5 Isolated from Human Colonic Flora Attenuates Intestinal Inflammation. Diseases of the Colon & Rectum, 53, 1676-1686.
<br>https://doi.org/10.1007/DCR.0b013e3181f4b148Singhal, N., Maurya, A.K., Mohanty, S., Kumar, M. and Virdi, J.S. (2019) Evaluation of Bile Salt Hydrolases, Cholesterol-Lowering Capabilities, and Probiotic Potential of Enterococcus faecium Isolated from Rhizosphere. Frontiers in Microbiology, 10, 1567. <br>https://doi.org/10.3389/fmicb.2019.01567Vimont, A., Fernandez, B., Hammami, R., Ababsa, A., Daba, H. and Fliss, I. (2017) Bacteriocin-Producing Enterococcus faecium LCW 44: A High Potential Probiotic Candidate from Raw Camel Milk. Frontiers in Microbiology, 8, 865. <br>https://doi.org/10.3389/fmicb.2017.00865Nami, Y., Abdullah, N., Haghshenas, B., Radiah, D., Rosli, R. and Khosroushahi, A.Y. (2014) Probiotic Assessment of Entero-coccus durans 6HL and Lactococcus lactis 2HL Isolated from Vaginal Microflora. Journal of Medical Microbiology, 63, 1044-1051. <br>https://doi.org/10.1099/jmm.0.074161-0Anadon, A., Martinezlarranaga, M.R. and Martinez, M.A. (2006) Probiotics for Animal Nutrition in the European Union. Regulation and Safety Assessment. Regulatory Toxicology and Pharmacology, 45, 91-95.
<br>https://doi.org/10.1016/j.yrtph.2006.02.004Liao, S.F. and Nyachoti, M. (2017) Using Probiotics to Improve Swine Gut Health and Nutrient Utilization. Animal Nutrition, 3, 331-343. <br>https://doi.org/10.1016/j.aninu.2017.06.007Sukegawa, S., et al. (2014) Effects of Oral Administration of Heat-Killed Enterococcus faecium Strain NHRD IHARA in Post-Weaning Piglets. Animal Science Journal, 85, 454-460. <br>https://doi.org/10.1111/asj.12163程首涛, 冯媛媛, 高敏, 仇天雷, 孙艳梅, 王旭明. 饲喂粪肠球菌对断奶仔猪粪便与猪舍气溶胶中细菌群落结构的影响[J]. 家畜生态学报, 2019, 40(10): 72-77.刘军, 彭众, 喻礼怀, 董丽. 屎肠球菌对AA肉鸡肠道酶活和绒毛形态的影响[J]. 中国家禽, 2020, 42(2): 64-68.安文艺, 雷佳琦, 董元洋, 武威, 刘璇, 邵玉新, 等. 壳寡糖与屎肠球菌对肉仔鸡生长性能、免疫功能及肠道短链脂肪酸含量的影响[J]. 中国畜牧杂志, 2019, 55(8): 110-117.Satish Kumar, R., et al. (2011) Purification and Characterization of Enterocin MC13 Produced by a Potential Aquaculture Probiont Enterococcus faecium MC13 Isolated from the Gut of Mugil cephalus. Canadian Journal of Microbiology, 57, 993-1001. <br>https://doi.org/10.1139/w11-092鞠安琪, 谷巍, 张海朋, 曲磊, 张冬星, 陈龙, 等. 屎肠球菌对鲤鱼非特异性免疫酶活性和抗病力的影响[J]. 中国兽医科学, 2018, 48(2): 228-233.陈志娜, 裴纪柳, 叶韬, 薛咏振, 詹志强, 李雅, 等. 泡菜源屎肠球菌Enterococcus faecium R2的环境胁迫耐受性及安全性评价[J]. 食品与发酵工业, 2019, 45(22): 32-38.