冠状动脉CT血管造影(computed tomographic angiography, CTA)因其检查简单、无创已作为无创筛查冠心病的首选技术手段,但其仍存在诊断特异性较低,仅限于解剖学水平,且有高估狭窄程度的倾向。而随着CT技术的蓬勃发展,CT心肌灌注成像(CT-based myocardial perfusion imaging, CTP)技术已经开始成熟,能更为准确地反映冠状动脉狭窄的血流动力学变化,同时反映心肌微循环情况,评价心肌灌注分布、心室功能,得到心肌的生理学和功能学信息。本文通过分析高原心脏病发病机制及心肌CT灌注成像技术在高原心脏病中的应用进行综述。
Coronary artery CT angiography (computed tomographic angiography, CTA) has been used as the preferred technical means for noninvasive screening for coronary heart disease because of its sim-ple and non-invasive examination, but it still has low diagnostic specificity, limited to anatomical level, and a tendency to overestimate the degree of stenosis. With the vigorous development of CT technology, CT myocardial perfusion imaging (CT-based myocardial perfusion imaging, CTP) tech-nology has begun to mature, which can more accurately reflect the hemodynamic changes of coro-nary artery stenosis, reflect the myocardial microcirculation, evaluate the myocardial perfusion distribution and ventricular function, and obtain the physiological and functional information of myocardium. This paper analyzes the pathogenesis of altitude heart disease and the application of myocardial CT perfusion imaging in plateau heart disease.
高原心脏病,CTP,静态CT心肌灌注成像,动态CT心肌灌注成像, High Altitude Heart Disease CT-Based Myocardial Perfusion Imaging Static CT for Myocardial Per-fusion Imaging Dynamic CT for Myocardial Perfusion Imaging摘要
Received: Apr. 18th, 2022; accepted: May 13th, 2022; published: May 19th, 2022
ABSTRACT
Coronary artery CT angiography (computed tomographic angiography, CTA) has been used as the preferred technical means for noninvasive screening for coronary heart disease because of its simple and non-invasive examination, but it still has low diagnostic specificity, limited to anatomical level, and a tendency to overestimate the degree of stenosis. With the vigorous development of CT technology, CT myocardial perfusion imaging (CT-based myocardial perfusion imaging, CTP) technology has begun to mature, which can more accurately reflect the hemodynamic changes of coronary artery stenosis, reflect the myocardial microcirculation, evaluate the myocardial perfusion distribution and ventricular function, and obtain the physiological and functional information of myocardium. This paper analyzes the pathogenesis of altitude heart disease and the application of myocardial CT perfusion imaging in plateau heart disease.
Keywords:High Altitude Heart Disease, CT-Based Myocardial Perfusion Imaging, Static CT for Myocardial Perfusion Imaging, Dynamic CT for Myocardial Perfusion Imaging
韦 楠,孙艳秋. 心肌CT灌注成像技术在高原心脏病中的应用进展Progress of Myocardial CT Perfusion Imaging in Plateau Heart Disease[J]. 临床医学进展, 2022, 12(05): 4264-4268. https://doi.org/10.12677/ACM.2022.125617
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