糖尿病的患病率呈现逐年上升的趋势,其中罹患2型糖尿病的人群占到总糖尿病患病人数的90%,而在糖尿病患者中超重人群占比约41%、肥胖人群占比约24.3%,早期诊断,早期干预肥胖与2型糖尿病对于人类的健康非常重要。miR-122在肥胖及2型糖尿病发生发展中具有重要的调控作用,且具有一定的诊断性能。本文主要针对miR-122在肥胖以及2型糖尿病相关方面的研究进展进行阐述。
The prevalence of diabetes is on the rise year by year. The people suffering from type 2 diabetes account for 90% of the total diabetes patients. Among diabetes patients, overweight people account for about 41% and obese people account for about 24.3%. Early diagnosis and early intervention of obesity and type 2 diabetes are very important for human health. miR-122 plays an important reg-ulatory role in the occurrence and development of obesity and type 2 diabetes, and has certain di-agnostic performance. This article focuses on the research progress of miR-122 in obesity and type 2 diabetes.
miR-122,肥胖,2型糖尿病,研究进展, miR-122 Obesity Type 2 Diabetes Research Progress摘要
The prevalence of diabetes is on the rise year by year. The people suffering from type 2 diabetes account for 90% of the total diabetes patients. Among diabetes patients, overweight people account for about 41% and obese people account for about 24.3%. Early diagnosis and early intervention of obesity and type 2 diabetes are very important for human health. miR-122 plays an important regulatory role in the occurrence and development of obesity and type 2 diabetes, and has certain diagnostic performance. This article focuses on the research progress of miR-122 in obesity and type 2 diabetes.
Keywords:miR-122, Obesity, Type 2 Diabetes, Research Progress
潘路路,林 波,马小莉,王 蕾,左 丹,赵慧琛,刘元涛,张玉超. MicroRNA-122在肥胖及2型糖尿病中的研究进展Research Progress of MicroRNA-122 in Obesity and Type 2 Diabetes[J]. 临床医学进展, 2022, 12(06): 5706-5712. https://doi.org/10.12677/ACM.2022.126824
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