乳胶过敏是一个容易被忽略的公共卫生问题,我国的发病率及患病率持续上升。乳胶过敏的临床表现可以从轻微的皮肤病变到危及生命的反应,如皮肤荨麻疹和致死性的过敏性休克等,其过敏机制至今未被完全认识。乳胶产品在日常工作中起到了很重要的作用,特别是医护人员的工作环境。本文从乳胶过敏的流行病学、临床表现、诊断、治疗、预防加以叙述,以提高对乳胶过敏的系统认识,可以更有效的预防此类过敏现象。
Latex allergy is a public health problem that is easily overlooked, and the incidence and preva-lence of China continue to rise. The clinical manifestations of latex allergy can range from minor skin lesions to life-threatening reactions such as skin urticaria and fatal anaphylactic shock, and the mechanism of allergy has not been fully understood. Latex products play an important role in daily work, especially in the working environment of medical staff. This article describes the epidemiology, clinical manifestations, diagnosis, treatment, and prevention of latex allergy, so as to improve the systematic understanding of latex allergy and can more effectively prevent such allergies.
Received: Jul. 17th, 2022; accepted: Aug. 16th, 2022; published: Aug. 23rd, 2022
ABSTRACT
Latex allergy is a public health problem that is easily overlooked, and the incidence and prevalence of China continue to rise. The clinical manifestations of latex allergy can range from minor skin lesions to life-threatening reactions such as skin urticaria and fatal anaphylactic shock, and the mechanism of allergy has not been fully understood. Latex products play an important role in daily work, especially in the working environment of medical staff. This article describes the epidemiology, clinical manifestations, diagnosis, treatment, and prevention of latex allergy, so as to improve the systematic understanding of latex allergy and can more effectively prevent such allergies.
IgE检测和免疫CAP检测用于诊断IgE介导的乳胶过敏的血清学方法。Hev b变应原以重组形式提供,可用免疫CAP检测。某些变应原(Hev b1, Hev b5, Hev b6.01, Hev b6.02)的致敏可以导致明显的临床症状,表现为真正的乳胶过敏。某些(Hev b8)成分的致敏通常会表现为轻症,甚至假阴性 [19]。嗜碱性细胞活化实验可以用于评估经乳胶刺激后的细胞活跃程度。有助于评估人体免疫系统的反应情况 [32]。
董胜璞,邱 健. 医护人员乳胶过敏的研究进展Research Progress on Latex Allergy in Medical Staff[J]. 临床医学进展, 2022, 12(08): 7815-7823. https://doi.org/10.12677/ACM.2022.1281126
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